Christodoulos floudas, the Stephen C. Macaleer ’63 Professor in Engineering and Applied Science, and Princeton engineering doctoral student Meghan Bellows-Peterson have developed a way of using mathematical models to identify potential drugs for fighting HIV.
Collaborating with researchers at the Johns Hopkins University School of Medicine, Floudas and Bellows-Peterson combined concepts from optimization theory with computational biology to take some of the guesswork out of discovering new drugs.
Using their program, the researchers were able to find a way of selecting peptides that could fit a binding site on HIV.
The program uses a more sophisticated method to sort through millions of possible peptides to identify the few which show potential, which reducing the amount of time and resources it takes to find new drugs.
The team’s findings were reported in the Nov. 17, 2010 issue of “Biophysical Journal.” The scientists hope to extend the use of their model to other diseases, particularly cancer.
Read More
Princeton boosts financial aid despite potential budget cuts, new endowment tax
Devon RudolphThe financial aid increase comes amid a rocky financial picture for many elite universities, which are confronting the loss of research federal funding and an endowment tax passed by Congress in July. It could also reduce Princeton’s tuition-paying student population.
Princeton's recent announcement of a boosted financial aid program could allow the University to be exempt from the recently passed federal endowment tax.
Town Council set to vote on immigrant sanctuary resolution following ICE raids
Justus Wilhoit and Leela HenslerThe Town Council will vote on a resolution affecting ICE cooperation at the meeting on Monday.
The Town Council will vote on a resolution affecting ICE cooperation at the meeting on Monday.
Alumni form mental health council in wake of student deaths
Luke GrippoThe council hopes to work with undergraduates to push for awareness about campus resources. At least four undergraduates at Princeton have died by suicide since 2022.
The council hopes to work with undergraduates to push for awareness about campus resources. At least four undergraduates at Princeton have died by suicide since 2022.