Kang’s lab, in trying to identify genes that contribute to differences among cancer patients receiving the same treatment, found that the gene metadherin (MTDH) produces a protein, which helps to increase the spread of cancer. Their subsequent research has revealed that the compound C26A6 reduces the interaction between MTDH and the protein SND1, which helps MTDH keep a specific shape that is central to its function. The two new studies in Nature Cancer show that C26A6 can stop cancer spread in mice with the next step seeking to study its effect on humans.
FROM THE PROSPECT: In acknowledgement of International Day of People with Disabilities, Associate News Editor Naomi Hess writes for the Prospect on her experiences as a disabled woman working to increase inclusivity and accessibility on Princeton’s campus. Hess commends work done by the University and the ‘Prince’ to increase accessibility on campus but states that “there’s still so much work to be done to make the campus better. Many physical infrastructure barriers remain, like unnavigable sidewalks and inaccessible dorms. Professors could be better about understanding medical needs, student groups and eating clubs could do more to include disabled students, and housing accommodations could always be improved.”
